Abstract

![Graphic][1]</img> Two thousand twenty-two has been the year in which the COVID-19 pandemic has receded leaving us with a substantial number of important investigations on the disease and the interactions between neuroinflammatory disorders and SARS-CoV-2 infection or vaccinations. This Year in Review, which in fact covers 2021 and 2022, includes many of these studies and others focused on different topics that have attracted the attention of N2 readers. These studies have been selected by the editors and reflect the broad range of topics covered in N2 . That our contributors accomplished these studies while facing the challenges presented by the pandemic demonstrates their commitment to the continued advancement of knowledge that will surely lead to improving the lives of our patients and to a healthier community in general. We have grouped the studies in 6 general themes including paraneoplastic and autoimmune encephalitis, MOG antibody–associated disease (MOGAD), neurologic diseases associated with IgG4 autoantibodies, COVID-19–related studies in the context of neurologic autoimmunity, other infectious diseases of the nervous system, and inflammatory mechanisms in neurodegenerative diseases. The first … [1]: /embed/inline-graphic-1.gif

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