N-vinylation of aromatic sulfonamides using calcium carbide as a concise solid alkyne source

Abstract

An efficient method for N-vinylation of aromatic sulfonamides using calcium carbide as a concise solid alkyne source is described. A series of N-vinyl aromatic sulfonamides are easily synthesized by this strategy. Notable features of this protocol are the use of an inexpensive and easy-to-handle solid alkyne source instead of flammable and explosive gaseous acetylene, transition metal-free catalysts, good functional group tolerance, and simple workup procedures. The synthesis of representative product can also be extended to gram scale.