Abstract
The title compound {systematic name: 1-[(1R,4aS,10aR)-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl]-N,N-dimethylmethanaminium chloride ethanol monosolvate}, C22H36N+·Cl−·C2H6O, was synthesized from dehydroabietylamine by N-methylation with formaldehyde/formic acid and transformation into the hydrochloride. The dehydroabietyl moiety exhibits the usual conformation with the two cyclohexane rings in chair and half-chair conformations and a trans-ring junction. The crystal structure is built up from columns of the dehydroabietyl moieties stacked along the a axis. These columns are held together by the chloride ions via N—H⋯Cl and C—H⋯Cl interactions, which establish a two-dimensional network parallel to (010). The ethanol solvent molecules are located between the columns and anchored via O—H⋯Cl hydrogen bonds.
Highlights
The title compound {systematic name: 1-[(1R,4aS,10aR)-7isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl]-N,N-dimethylmethanaminium chloride ethanol monosolvate}, C22H36N+ÁClÀÁC2H6O, was synthesized from dehydroabietylamine by N-methylation with formaldehyde/ formic acid and transformation into the hydrochloride
The dehydroabietyl moiety exhibits the usual conformation with the two cyclohexane rings in chair and half-chair conformations and a trans-ring junction
The crystal structure is built up from columns of the dehydroabietyl moieties stacked along the a axis
Summary
The title compound {systematic name: 1-[(1R,4aS,10aR)-7isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl]-N,N-dimethylmethanaminium chloride ethanol monosolvate}, C22H36N+ÁClÀÁC2H6O, was synthesized from dehydroabietylamine by N-methylation with formaldehyde/ formic acid and transformation into the hydrochloride. The crystal structure is built up from columns of the dehydroabietyl moieties stacked along the a axis. These columns are held together by the chloride ions via N—HÁ Á ÁCl and C—HÁ Á ÁCl interactions, which establish a two-dimensional network parallel to (010). Related literature For the biological activity of dehydroabietylamine derivatives, see: Goodson et al (1999); Rao et al (2008); Wilkerson et al (1993); For the crystal structures of dehydroabietic acid derivatives, see Rao et al (2006, 2009)
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