N-glycans from human milk glycoproteins are selectively released by B. infantis EVC001 in vivo.

Abstract

Both free oligosaccharides (human milk oligosaccharides) and conjugated glycans (N-linked) are present in human milk. These indigestible carbohydrates found in human milk shape the gut microbiome of breastfed infants. The complexity of these glycans restricts their utility to a limited number of bacteria that can access these carbohydrates as a sole carbon source. Infant-associated Bifidobacterium, such as Bifidobacterium longum subsp. infantis (B. infantis), are among the bacteria that are able to utilize these glycans. The activity of …