Abstract
AbstractThe iridium catalysed N‐alkylation of α‐amino esters and amides using alcohols through hydrogen borrowing has been developed. The protocol can be applied to both the free base and hydrochloride salts of the amines and produces water as the only by‐product. This transformation can provide easy access to chiral N‐alkyl amines from readily available starting materials in a simple one step reaction.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
