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Abstract

Garcinia mangostana L. or mangosteen of the Clusiaceae has traditionally been employed as medicinal drugs for decades. A plethora of compounds are responsible for a wide range of medicinal properties and biological activities. The ethanol extract of the mangosteen rind has been found to be anti-inflammatory, antioxidant and anti-acne-causing bacteria. Many research studies have confirmed its potency, with the ethanol extract of the rind being able to inhibit pro-inflammatory cytokines (TNF- α ) at relatively low concentration. DPPH assay also revealed its potent radical scavenging activity. The compound responsible for the antibacterial activity, a-mangostin, was especially potent and one of the compounds responsible for the anti-bacterial activity.