Abstract

Changes in bacterial flora in the tympanic cavity following tympanomastoidectomy were studied in 98 ears of 94 patients suffering from chronic otitis media with continuous otorrhea. Materials were collected preoperatively from the tympanic cavity with a cotton swab through the external auditory canal and postoperatively from the cavity with a draining tube placed through the hypotympanotomied space during the operation. The draining tube was removed 4 to 12 days after surgery and subjected to bacteriological study. In spite of the intensive use of various antibiotics to which the isolated bacteria were sensitive, some of the bacteria remained in the tympanic cavity. The incidence of representative bacteria before and after surgery were as follows: Staphylococcus aureus in 41 and 5 ears, Pseudomonas aeruginosa in 24 and 10 ears, Staphylococcus epidermidis in 24 and 9 ears and Corynebacterium in 23 and 3 ears, respectively. These results suggest that the postoperative use of antibiotics for 4 to 12 days is not always sufficient to eliminate bacteria in the tympanic cavity, especially in cases of Pseudomonas aeruginosa infection.

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