Abstract
We have applied microwave regional coagulation therapy (MRC) to urinary bladder cancer as anew bladder preserving procedure. This paper describes histological findings of the bladderspecimens which were obtained by transurethral resection or total cystectomy after MRC.Immediately after MRC, heat effect of microwaves was recognized even in the deep muscle layer of the bladder and carcinoma cells were completely necrotized while papillary structure with congested vessels was observed. Histological examination also revealed that granulation formations existed 3 months after MRC and fibrotic changes existed 6 months after MRC in the coagulated regions. However, perforation of the bladder was not evident in all cases. These results indicated that MRC might be a safe and effective procedure for bladder cancer.
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