フッ化物局所応用ならびに飲料水中フッ素による永久歯う蝕予防効果の比較

Abstract

The purpose of this study was to compare the caries prevalence and incidence between 6-year-old lifelong residents in a natural fluoride area (0.74-1.10ppm F: NF group) and participants in school-based fluoride mouthrinsing (FR group) or usage of SnF2 dentifrice (FD group). The FR group rinsed daily with 0.05% NaF solution for 3.5 years and the FD group used 0.41% SnF2dentifrice for 3 years beginning at the age of six.Mean DMFT in the NF group (n=58) from the age of 6 to 9 was significantly lower (p<0.05, p<0.01) than that of both the FR (n=78) and the FD group (n=73) at all of the ages examined. Only 1-year mean DMFT increments from the age of 6 to 7 in the NF group (0.24±0.67) were significantly different (p<0.01) from the FR group (0.67±0.98) and the FD group (0.71±0.89). No statistical differences of mean DMFT increments, however, were found between any pairs of study groups after 2 or 3 years from the baseline. Incremental DMFT rates on first molars in the NF group were significantly lower (p<0.05, p<0.001) than those in the FR or FD group both after 1 and after 2 years.The results of the present study demonstrate that lifelong residents in a natural fluoride area experienced significantly fewer caries than those who received topical fluoride application. However, the differences of caries increments between the FW group and the FR or FD groups diminished with the passage of time.