Abstract
Catheter-related bloodstream infection (CRBSI) is one of the serious complications of chemotherapy in various cancer treatments and often causes cessation or temporary withdrawal of treatment. We investigated CRBSIs associated with retrograde superselective intra-arterial chemoradiotherapy for oral cancer. A total of 160 patients with oral cancer who had received catheterization from the superficial temporal or occipital arteries to the tumor-feeding arteries in our institution between January 2010 and December 2014 were studied retrospectively. All intra-arterial catheter tips were sent for culture, and catheter bacterial cultures were positive in 67 patients (41.9%). Blood culture tests were performed in 50 patients who had fever with a temperature of 38℃ or higher, and blood cultures were positive in 20 patients (12.5%). Both catheter cultures and blood cultures were positive in 12 patients. The same bacteria were detected in 7 patients (4.4%), fulfilling the criteria for CRBSI. The incidence ratio of CRBSI was 0.83 per 1,000 catheter days. All CRBSIs were eventually controlled by appropriate antimicrobial therapy and catheter replacement or decannulation.
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