Abstract
Arginine treatment was performed on four cows with ketosis and two healthy cows. Other cows were treated with dexamethazone. Each cow received 320g of arginine or 20mg of dexamethazone into the jugular vein. After infusion, blood samples were collected 9-13 times from this vein to determine pancreatic insulin (IRI) and glucagon (IRG), and blood glucose and lipid components.Low responses of IRG and IRI were observed on two of the four cows affected with ketosis. They were also observed in the healthy cows and the other two affected cows after having recovered from ketosis. One of the affected cows showed extremely high levels of IRG and IRI after arginine treatment. Response of IRI was later than a rise in glucose in the affected cows treated with dexa-methazone, as compared with the healthy ones.From the results mentioned above it seemed that ketosis might be related to hormonal disturbance in glucose metabolism.
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