Abstract

Innervation patterns of primary vestibular neurons in the guinea pigs utricle were examined with the HRP method. Nerve fibers which do not bifurcate connect with type I hair cells in the striola. Nerve fibers which bifurcate connect with type I and type II hair cells throughout the utricular maculae.Single neuron physiology was investigated in the superior vestibular ganglions. Irregularly firing neurons with higher coefficience of variation (CV) had higher gain to tilt. Among the lateral tilt reactive neurons, ipsilateral tilt neurons were greater in number than contralateral neurons, but this tendency was seen only in regularly firing neurons and not in irregularly firing ones.Single cellular HRP studies of neurons identified electrophysiologically as of otolith origin showed that primary utricular neurons which do not bifurcate and connect with type I hair cell are irregularly firing neurons with a higher gain for tilt.

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