Abstract
A poliomyelitis virus strain was isolated by intracerebral and nasal administration on monkey from the spinal cord of a paralytic poliomyelitis case died in Scptember, 1950 in Tokyo, which was stored in dry ice until the day of inoculation in March, 1952. The spinal cord of the sacrificed monkey was successfully transfered to mouse by intracerebral inoculation.The mouse adapted Tokyo strain was applied to the neutralization test against each immune monkey serum of Lansing, Brunhide, Leon, B-34 (a type 2 poliomyelitis virus, recovered in Tokyo, 1948, using mouse only.) and also of Tokyo strain. The result of the neutralization test showed that the newly mouse adapted Tokyo strain was well neutralized by the immune sera of Lansing, Tokyo and B-34, and hardly neutralized by Brunhilde and Leon immune sera. Hence it is understood that mouse adapted Tokyo strain is to belong to type 2 together with B-34 and Kawasaki strains.At the brain passage, the harmonic mean of the incubation period of this Tokyo strain is 5.4 days which shows 2 days shortening, comparing with that of Lansing strain which is 7.3 days.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
