Abstract

It is well known that antibiotics and nitrofuran derivatives promote the growth and prevent or cure the disease of domestic animals. Some of these agents are also reported to have a curative effectiveness on fish diseases. However, many studies1) have shown that antibiotics have no growth promoting effect on trout. There have been no previous studies on the growth promoting effect of nitrofuran derivatives for fish. This current study deals with the effects of furazolidone, N-5-nitro-2-furfurylidene-3-amino-2-oxazolidone, on the growth and on the feed efficiency of red sea bream, Chrysophyrys major. The results obtained can be summarized as follows: (1) Furazolidone promoted the growth of red sea bream with higher feed efficiency. The growth and the feed efficiency of fish fed 0.01% level furazolidone were best, and those fed 0.1% level were less than those of the control group (Table 2 and Fig. 1). (2) The protein and fat contents of the dorsal muscle of fish fed furazolidone were nearly identical to those of the control fish (Table 3). (3) The differences between the ratio of the weight of liver, heart, kidney and milt to body weight of furazolidone fed fish and those of control fish were insignificant (Table 4).

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