Abstract
Persistence of antibodies against rabies virus was studied in house-held dogs vaccinated with an inactivated tissue culture rabies vaccine. Moreover, neutralizing antibody (NAb) titers to rabies virus were surveyed in 942 sera collected from house-held dogs in Fukuoka city during a 1986-1989 period and in 149 sera collected from retained stray dogs in Kumamoto and Miyazaki prefectures during a 1986-1987 period.The geometric mean NAb titers at 1, 6, and 12 months postvaccination were 1: 137.2, 1: 59.3, and 1: 26.0, respectively. All of the serum samples collected at 12 months post-vaccination retained a NAb titer level of 1: 4 or more.The geometric mean NAb titers in house-held dogs and retained stray dogs were 1: 18.4 and 1: 6.0, respectively. The difference in the titer was statistically significant. The rate of serum samples showing NAb titer of 1: 4 or more was 62.4% in the house-held dogs, and the rate was significantly higher than that in the retained ones (31.5%).
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More From: Journal of the Japan Veterinary Medical Association
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