健常女性における最大下運動時の二重積屈曲点と動脈スティフネスの関係

Abstract

The purpose of this study was to elucidate the relation between double product break point (DPBP) and pulse wave velocity (PWV).Two hundred three healthy Japanese females were studied (mean age; 53.5 +/- 11.7 years old). The DPBP was measured by continuous incremental exercise test with a bicycle ergometer (ML-3600, Fukuda Electronic Co. Ltd). The work rate at DPBP was converted into metabolic equivalents (METs@DPBP). The brachial-ankle PWV (baPWV) was also measured. In addition, height, weight and mean blood pressure (mBP) were measured and physical activity condition in daily life (PA) was evaluated by questionnaire.The mean METs@DPBP was 5.0 +/- 0.7 METs. The mean baPWV was 1,373 +/- 254 cm/ sec. The relation between METs@DPBP and baPWV was investigated with the use of multiple linear regression models with adjustment for affecting factors of baPWV.In this study, it was identified that there was a significantly inverse relation between METs@DPBP and baPWV (p <0.01). This finding was independent from age, height, weight, mBP and PA. Thus, there was an inverse relation between sub-maximal aerobic capacity and arterial stiffness.