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Abstract
We encountered a case of maxillary carcinoma with intracranial invasion complicated by the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) which occurred following carbamazepine administration for meningitis. A 55-year-old female with maxillary carcinoma with intracranial invasion had been treated for increased intracranial pressure by steroids and glycerol. The antidiuretic hormone level was not suppressed by hypoosmolality of the plasma and alpha-human atrial natriuretic poly-peptide was within the normal range. She did not regain consciousness and died of cachexia four months later.
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