冠動脈造影後に生じる副作用に関する調査

Abstract

We investigated 468 inpatients for adverse reactions occurring after they underwent coronary angiography (CAG) according to the specified clinical path in the cardiology department of our hospital. Upon interviewing the patients we noted that about 20% of them had symptoms like headache, nausea, vomiting, and giddiness.Though such symptoms were more prevalent in women and patients who had a history of allergic reactions to medicines, no correlation was found between symptom occurrence rates and age, type of contrast media used or dosage. These adverse effects occurred one hour or more after undergoing CAG. The rate of occurrence for such delayed reactions was 37 % in the patients in whom they were observed and 7.6% for all patients. Although these adverse effects were assumed to be mainly due to contrast media, the possibility of them being due to other drugs could be not be ruled out. However, symptoms were very similar to those for delayed adverse reactions of contrast media reported in the past.Unexpected adverse reactions due to contrast media will continue to occur and may be serious so patients should be carefully observed following CAG.