耐糖能低下例における血糖値と血清脂質との関係

Abstract

By the criteria of 75g OGTT, glucose intolerances such as diabetic type and borderline type were determined in cases aged 30 to 70 years.1) The decrements of FBS during the periods of 4 months were accompanied by the decrements of serum cholesterol or triglyceride levels in 68 male cases with diabetes mellitus.2) There were no correlations between FBS and serum cholesterol, triglyceride, HDL cholesterol, HDL-C/Chol, apoproteins A-I, A-II or B, nutritional intakes or fat energy ratio in 63 male or female cases with glucose intolerance. But there was a negative correlation between FBS and protein energy ratio. On the other hand there was a positive correlation (r=0.88) between HbA1c and FBS measured one month before. There was a positive correlation between HbA1c and carbohydrate energy ratio, while a negative one between HbA1c and A-I or protein energy ratio. Therefore it is desirable for improving blood sugar control to decrease carbohydrate energy ratio and to increase protein energy ratio.3) There were positive correlations between relative body weight ratio and serum cholesterol or triglyceride, between the rate of body weight changes and FBS, and between the rate of body weight changes and ingested energy or carbohydrate volumes to the prescribed ones in 110 male or female cases with glucose intolerance. There was also a positive correlation between the rate of body weight changes and carbohydrate energy ratio, while a negative one between that and protein energy ratio. Therefore it is desirable for the decrement of body weight to decrease the intakes of energy or carbohydrate and to increase protein energy ratio.4) More than 80 kcal of alcohol per day resulted in poor blood sugar control in 50 male cases with glucose intolerance. Serum triglyceride or γGTP levels tended to increase by drinking alcohol beverages everyday in obese cases with glucose intolerance.