硬口蓋原発の悪性筋上皮腫例

Abstract

Malignant myoepithelioma is a rare tumor that occurs in about 0.2% of the salivary gland tumors. We report herein on a case of malignant myoepithelioma which presented in the hard palate.The patient was a 54-year-old woman, who visited our outpatient clinic with a complaining of nasal obstruction. Rhinology showed an elevation of the nasal cavity floor, and a 15 mm mass lesion was observed in hard palate.The presence of tumor was confirmed by CT imaging on which a large solid mass occupying part of right maxillary sinus, hard palate, and nasal cavity were observed. There were no palpable neck lymph nodes. The pathological diagnosis of a biopsy taken from the nasal cavity floor was malignant myoepithelioma. Immunohistochemical studies showed positive staining for keratin and p63, and partial positivity for S-100 and GFAP.The patient underwent subtotal maxillectomy of the right maxilla and partial maxillectomy of the left maxilla.In a 2-year follow up after the surgery, there has been no evidence of recurrence.