精神分裂症患者心理理论加工的特点及其脑机制

Abstract

近年来，对精神分裂症患者社会认知的研究越来越多，其中对精神分裂症患者心理理论的研究成为热点。研究一致发现，精神分裂症患者心理理论能力受损，他们心理理论的缺陷与其症状有关。内侧前额叶皮层、杏仁核和顶下叶三个脑区涉及精神分裂症患者的心理理论障碍。另外，精神分裂症患者情绪加工和面孔识别困难，而大脑偏侧性被认为是造成以上困难的原因之一。在未来，还需要对精神分裂症患者的脑功能成像、测量工具等方面努力。 In recent years, there were more and more researches talking about the social cognition of schi-zophrenic patients, and the theory of mind (TOM) became a hot topic. TOM was consistently found to be impaired in schizophrenic patients and the TOM defects were concerned with their symptoms. There were three key regions involved in the TOM deficits which were seen in schizophrenic patients: the medial prefrontal cortex (MPFC), the amygdala, and the inferior parietal lobe (IPL). In addition, brain lateralization was one reason for emotional cognition and facial recognition deficits. For future research, we should pay more attention to functional brain neuroimaging and evaluation instruments of TOM in schizophrenic patients.