早期舌癌の治療成績

Abstract

In our hospital, 29 cases of early stage tongue cancer (maximum tumor size < 3cm, NOMO) were treated between May 1987 and December 1997. Twenty two cases (T1; 20 cases, T2; 2 cases) were treated with radiotherapy (RT group), and 7 cases (T1; 4 cases, T2; 3 cases) with partial glossectomy (OP group). Radiotherapy was performed using external sources of radiation (2 Gy/day, total dose; 50-70 Gy, average; 65.3 Gy). The partial glossectomy was performedwith removal of the tumor including a safety margin of 10 to 15 mm. In the RT group, the tumors persisted locally after the radiotherapy in 6 cases and recurred locally in 9 cases. In the OP group, neither recurrent nor residual tumors were found in any of the cases. The tumors were controlled more effectively in the OP group than in the RT group (Fisher's exact probability test; P=0.05). There were however, no significant differences in the 5-year survival rate of the two groups of patients by the Kaplan-Meier's method: RT group (82.9%) and OP group (75.0%). From the perspective of local control, although the survival rate of the OP group was slightly lower, the partial glossectomy seems to be more effective treatment for early stage tongue cancer than external radiation.