舌癌に対する電子線腔内昭射８症例と文献的考察

Abstract

The clinical results of electron beam therapy using intraoral cone in 8 cases of primary and recurrence carcinoma of tongue (T 1 and smaller T 2) were reported. The primary and recurrence cases were 5 and 3, respectively. In the 5 cases, a total dose of 10-30 Gy external radiation therapy were combined prior to electron beam therapy.The total dose of electron beam therapy varied from 40 to 60 Gy. In all cases, tumor showed good response and disappeared clinically. Radiation stomatitis, pain of the tongue with masticatory disturbance due to tenderness were complicated in all cases. These complications gradually disappeared 2 to 6 months after treatment. However, loss of body weight and bone exposure were not recognized in any case. Intraoral-cone electron beam therapy is thought to be available and has less complications comparing interstitial irradiation therapy from the review of literature. Within 6 months after radiation, submandibular lymphnode metastasis occured in 2 patients and radical neck dissection was performed. During the follow up period (from Feb. 1986 to Oct. 1988), 6 out of 8 cases are now NED (no evidence of disease).The advantages of this therapy should constitute; 1) less exposure of irradiation in another site, and 2) less complications comparing external beam therapy and interstitial irradiation. However, indications were limited according to the site and size of the tumors.