Abstract
Serum levels of digoxin and methyldigoxin were measured with the cloned enzyme donor immunoassay (CEDIA) method and the fluorescence polarization immunoassay (FPIA) method.In other samples, both of those cardiac glycosides were measured with FPIA method and radioimmunoassay (RIA) method.There was a significant correlation (r=0.835, n=85) between CEDIA and FPIA methods in serum levels of digoxin and an apparent that of methyldigoxin. But in some patients, especially in infants, the values of the CEDIA method were lower than those of FPIA method.In contrast, there was a higher significant correlation (r=0.939, n=63) between FPIA and RIA methods in serum levels of both cardiac glycosides.These results may indicate that sensitivities of these methods to the interfering substances (ex. endogenous digoxin-like substance) differ each other.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
