Abstract

Using transparent specimens and serial sections prepared from lower leg bones, humerus. and forearm bones of sixty human foetuses age ranging from second embryonic month to the last, after injection of dye, the construction of medullary blood vessels and canals of cartilage have been studied and the following are the results.1. The time of bone marrow growth and the appearance time of nutrient arteries and veins are fixed in all these bones and it coincides with that in the femur.2. The number and site of nutrient foramen are generally fixed in respective bone.3. The direction of nutrient vessels penetrating through the bone wall is fixed in tibia; but in other bones it is not fixed and no regular changes according to monthly progress can be recognized.4. The manner of branching and the running of medullary arterial branches are fixed according to the shape of each bone, and there are anastomoses among arterial branches.5. The medullary venous system is consisted of main venous sinuses and venous meshworks communicated with these sinuses.6. Metaphyseal arteries, with exception in the proximal metaphysis of the radius, appear in the metaphysis of each bone during the period between the sixth and seventh embryonic months, and these arteries are anastomosed with branches of diaphyseal arteries.7. Canals of cartilage of each bone enter in a fixed order according to the size of respective epiphysis.

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