Abstract
At the SPring-8, we have developed and improved protein crystallography beamlines to achieve the data collection for High-Throughput Protein Crystallography. RIKEN Structural Biology Beamline I (BL45XU) is the first brunched Undulator beamline. The PX-station of BL45XU introduced the Trichromatic concept that optimizes for the multi-wavelength anomalous diffraction (MAD) method with three-colored and coaxial synchrotron X-ray beams. The concept enables rapid and flexible switching of three defined wavelengths and can be collected MAD data taking into account syatematic errors such as radiation damage. RIKEN Structural Genomics Beamlines (BL26B1 and BL26B2) have implemented the automatic operation for rapid data collection of a vast amount of protein crystals to contribute to the structural genomics research. The automation has been achieved by developing the centralized control software BSS. The nonstop data collections for multiple samples have been achieved by developing the new-concept sample changer SPACE. The automatic operation has been satisfactorily performed, for more than two years since 2003.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
