Abstract
The incidence of multiple primary cancers in the head and neck region has increased in recent years. While we often treat double cancers, triple or more primary cancers are rare. We report a case of metachronous quadruple primary cancer in the head and neck region of a 65-year-old man. The 1st cancer, a left tonsillar carcinoma was diagnosed in Sep.1993; the 2nd one, a tracheal carcinoma was in Jan. 1994; the 3rd, a lingual carcinoma, in Oct. 1995; and the 4th, a hypopharyngeal carcinoma, in Feb. 1997. All of the cancers were highly differentiated squamous cell carcinomas. All of tumors were resected curatively without lymph node imvolvement or distant metastasis.
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