Abstract
The ergot cultivated on rye contains several kinds of alkaloids. The alkaloids of ergotoxine-and ergometrine-group have been found in fluid-extract of such cultivated ergot. Therefore, the hysterotonic action of extract is due to these ingredients. Furthermore, the blood pressure of rabbit can be lowered, too. On the excised intestine of rabbit, the extract diminishes the tension and the amptitude of autonomic movement. The vasoconstrictor action can be seen by Laewen-Trendelenburg's method. The movement of perfused toad heart has been depressed by the extract. These several actions of extract are weakened with the lapse of time. The grade of weakening is proportional to the acidity of extract. The weakening can be protected by ascorbic acid in some extracts.
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