Abstract

The author studied clinical significance of auto-liver-antibody in liver diseases and obtained the following results.1. Auto-iiver-antibody in liver diseases shows decidedly stronger pesitive reaction than in other diseases, and in addition, it presents a higher titer of the antibody. Especially in the liver disease other than infectious hepatitis such as in liver cirrhosis it may be emphasized that the antibody titer is high.2. Auto-liver-antibody presents a close correlation with the liver functions and liver autopsy picture.3. Auto-liver-antibody is quite useful for differential diagnosis and prognosis of liver diseases.4. The mice previously sensitized wth homologous-liver-antigen or by albumin of eggwhite and attacked by Ectromelia virus are clearly at more disadvantage for the infection than in the case of non-sensitized mice. However, the difference between the two groups is not so distinct and the existence of liver-damaging action by the homologous- and auto-liver-antibodies can not be decided definitely.

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