外来患者に対する経口抗がん剤の薬歴管理導入の有用性

Abstract

Medication history management has been conducted for all patients in Kitasato Institute Hospital, Kitasato University, who were administered with injectable anticancer drugs; however, the medication history management of oral anticancer drugs was not adequately addressed. In this study, we started the medication history management for oral anticancer drugs that were administered, and investigated the usefulness of this practice. The medication history management of S1 and Capecitabine was started from May 2010, and in January 2011, the medication history management of all oral anticancer drugs, whose washout period was specified on the package, was started. The number and details of inquiries on the prescription of oral anticancer drugs between May 2009 and April 2011 were investigated. The number of the prescription inquiries after the introduction of the medication history management was 129, which was 6.5 times higher than that observed before the introduction. With respect to the details of inquiries, most inquiries were related to the “date of administration commencement” (61.2％), followed by the “duration of prescription,” “administration schedule,” and “dose” (9.3％, 8.5％, and 7.8％, respectively). These results suggest that introducing the medication history management can contribute greatly to assuring the efficacy and safety of drug treatment for cancer.