Abstract

Five cases of the pulmonary non-Hodgkin's lymphoma, B cell type were examined for clinicopathological, immunohistochemical and electron microscopical studies. We divided them into two groups. The first group had no symptomes and good prognosis. They were diagnosed as non-Hodgkin's lymphoma, diffuse, small cell or medium sized cell type. They histologically showed the typical “lymphoepithelial lesion” and less destructive infiltration with unclear margin of the tumor. The second group had pulmonary symtomes and poor prognosis with histology of non-Hodgkin's lymphoma, diffuse, large cell type. They showed destructive infiltration with relatively clear margin of the tumor and no lymphoepithelial lesion. There was some immunohistochemical difference between both groups. The former corresponded with MALT (muocsa-associated lymphoid tissue) lymphoma. The latter was an aggressive lymphoma and had much in common with features of nodal lymphomas. We concluded that a group of MALT lymphoma gave some characteristics of the pulmonary non-Hodgkin's lymphoma.

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