Abstract
We report two cases of breast cancer with head and neck metastasis. Case 1 was a 60-year-old woman undergoing left breast cancer mastectomy 13 years earlier, and seen for diplopia. Computed tomography (CT) and magnetic response imaging (MRI) showed an enhancing lesion filling the left sphenoid bone, necessitating endoscopic sinus surgery. Immunohistochemistry was positive for estrogen and progesterone receptors, yielding a diagonosis of breast cancer metastatic to the sphenoid bone. Case 2 was a 63-year-old woman undergoing right breast cancer mastectomy 7 years earlier, with chemotherapy and seen for a nasal obstruction. Endoscopy showed a nasopharyngeal tumor. Biopsied specimens confirmed breast carcinoma metastasis. Both cases required radiotherapy and hormonal therapy and as yet have shown no recurrence. The possibility of metastatic disease should thus be considered in those with a history of breast cancer.
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