いわゆる前立腺性好酸球増多症の研究

Abstract

Three typical cases of prostatic eosinophilia receiving an adrenal cortical hormone (Dexamethasone) were subjected to the massage of the prostate before, during and following the administration of the hormone and during the cessation. This paper deals with the results of the study designed to investigate the peepheral eosinocyte counts, blood pictures the PE phenomenon, and the Charcot-Leyden crystal forming capacity. The results are summarised as follows:1) When Decadrone (Dexamethasone) was given to patients who showed the PE-positive reaction, the eosinocyte count and blood picture became normal during and following the administration.The PE phenomenon also disappeared but the Charcot-Leyden crystalforming capacity was positive.2) Administration of Decadrone to PE-positive patients resulted in eosinophilia during the cessation of medication and following the administration. Blood was positive for the PE phenomenon and the Charcot-Leyden crystal-forming capacity.3) Peripheral eosinocyts from PE-positive patients were positive for the Charcot-Leyden crystal-forming capacity, irrespective of Decadrone administration and prostatic massage.4) Following Decaidrone administration, peripheral eosinocytes were positive for the Charcot-Leyden crystal-forming capacity, even though they became normal.5) Decadrone administration reduced the complaints of PE-positive patients markedly, but the complaints reappeared themselves when the administration was ceased.6) The etiology of so-called prostatic eosinophilia has not yet been identified, but it appears that besides infection by microorganisms and allergy due to focal infection, some abnormality in the reticuloendothelial system, including the marrow, should be taken into consideration.