Abstract
Temporal bone changes were noted in a 37-year-old man who developed acute bilateral deafness four months before death. The patient suffered from proteinuria and hematuria, so he had received prednisolone. Autopsy revealed non-Hodgkin's malignant lymphoma, membranous proliferative glomerulonephritis and necrotizing vasculitis of the middle-sized and small arteries. In the temporal bone study, inner ear changes were limited to the cochlea. The vestibular structures showed no detectable pathologic changes. These changes included total absence of the organ of Corti, atrophy or loss of the stria vascularis, collapse of Reissner's membrane in the middle turn and new bone formation in the apical turn. The arteries and nerves in the inner ear canal were normal.
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