Abstract
Carcinosarcoma originating in the salivary glands is rare, accounting for less than 1% of all malignant salivary gland tumors. We report a rare case of carcinosarcoma of the palatal minor salivary gland with fibrous dysplasia of bone. A 20 year-old man presented with a swelling on the palate. A detailed computed tomographic (CT) examination revealed that a tumor occupying the right maxillary sinus had destroyed the maxilla. The tumor was growing rapidly. It was histopathologically diagnosed as carcinoma in pleomorphic adenoma (carcinosarcoma type) on examination of biopsy specimens. The patient was treated surgically (total maxillectomy). Histopathological examination of the resected specimens confi rmed the diagnosis of carcinosarcoma with fibrous dysplasia of bone. No invasion of tumor cells was noted at the surgical margins, but local recurrence occurred 4 months after operation. The tumor invaded the brain, and the patient died 3 months after local recurrence. Autopsy revealed very extensive growth of the recurrent tumor cells, but no distant metastasis.
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