Abstract
We report a case of acute permeability pulmonary edema after the transfusion of fresh frozen plasma (FFP). The patient was a 68-year-old female who was transferred to our hospital for the treatment of subarachnoid hemorrhage. After clipping the aneurysm in the left middle cerebral artery, the patient developed a bleeding diathesis. Laboratory findings confirmed disseminated intravascular coagulopathy (DIC). After the transfusion of FFP to treat the DIC, the febrile attacks recurred and were reduced by corticosteroids. At the time of the last febrile episode, dyspnea and hypoxia suddenly developed. The chest X-ray revealed alveolar opacities in the right upper and middle lung field without heart enlargement. The ultrasound cardiogram was normal. Based on the clinical course, the acute clinical features were considered to represent non-cardiogenic permeability pulmonary edema. Anti lymphocyte antibody was detected in the patient's serum. The leucoagglutination reaction was confirmed between the patient's serum and the FFP used on the day when the acute pulmonary edema occurred. Therefore, this reaction suggested the allergic permeability pulmonary edema. To prevent pulmonary edema after the transfusion of FFP, the use of a leucocyte reduction filter is considered effective in reducing the leucoagglutination reaction.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
