Abstract
Infrared absorption spectrum (2.5μm-10.0μm) of human atheromatous lesion and macroscopic normal region of abdominal aorta taken from cadavers were investigated. The absorption spectrum were measured by transmitting method with the samples which were sliced parallel to the surface of the intima. In addition, histopathological examination were performed for these samples stained by hematoxylin and eosin. The result is that the characteristic absorption peak was observed at 5.8μm in wavelength associated with the atheromatous lesion. It seems that the characteristic peak is due to the ester bond of cholesterol ester which is accumulated in the arterial wall. In laser angioplasty, use of this characteristic absorption peak is helpful not only to prevent arterial perforation by laser irradiation, but also to make a diagnosis of atheromatous lesion.
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More From: THE JOURNAL OF JAPAN SOCIETY FOR LASER SURGERY AND MEDICINE
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