Abstract
Radiofrequency ablation (RFA) was used to treat colorectal liver metastases, and the prognosis of hepatic resection with RFA (Hr + RFA, n = 15) was compared with that of hepatic artery infusion chemotherapy (HAI, n = 43) in patients with unresectable liver metastases. Hr + RFA group 4-year survival rate was 37.5%, and better than the HAI group 2-year survival rate of 13.4%. When local recurrence rate after RFA was determined for those with colorectal liver metastases (LM, n = 30) or hepatocellular carcinoma (HCC, n = 174), tumor diameter affected recurrence rate in neither group, though recurrence rate increased with tumor size. Our findings suggest that RFA is indicated for patients whose tumor diameter is 2 cm or less, since their recurrence rate should be lower. RFA thus appears useful for treating colorectal liver metastases.
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