几种中药提取液对小鼠抗疲劳和抗衰老作用的研究

Abstract

目的：探索四叶参、黄精、黄芪、楤木提取液对小鼠抗疲劳及抗衰老能力的影响。方法：将四叶参、黄精、黄芪、楤木经过烘干、粉碎后制备提取液；将小鼠分成高浓度组、低浓度组和对照组，分别灌胃四周后，观察小鼠负重游泳实验时间，检测小鼠肝糖原和肌糖原的含量和血清MDA的含量。结果：高浓度和低浓度的四叶参、黄精、黄芪、楤木提取液均能延长小鼠负重游泳的时间(P < 0.05)，增加肝糖原和肌糖原的含量(P < 0.05)，减少血清MDA的含量(P < 0.05)。结论：四叶参、黄精、黄芪、楤木提取液能增强小鼠的抗疲劳能力和抗氧化能力。 Objective: To study the effects of the lance asiabell root, rhizoma polygonati, astragalus membra-naceus and Cong wood extract on anti-fatigue ability and the ability of anti-aging in mice. Methods: The lance asiabell root, rhizoma polygonati, astragalus and Cong wood were dried, crushed and made extract; mice were divided into high concentration group, low concentration group and the control group. All group lavaged four weeks. After four weeks, the time of mice weight loaded swimming were tested, the content of liver glycogen and muscle glycogen and the content of serum MDA in mice were tested. Results: High concentration and low concentration of lance asiabell root, rhizoma polygonati, astragalus root and Cong wood extract can extend the weight loaded swimming time in mice (P < 0.05), increase the content of liver glycogen and muscle glycogen (P < 0.05), and decrease the content of serum MDA (P < 0.05). Conclusion: Lance asiabell root, rhizoma polygonati, astragalus root and Cong wood extract can enhance the ability to resist fatigue and oxidation resistance.