Abstract
In this study we used the trapezoid rotation test to evaluate vestibular function in normal guinea pigs or guinea pigs with peripheral vestibular disorder. Post-rotatory nystagmus (PRN) was recorded on videotape under dark conditions with an infrared charge-coupled device camera. The analysis was performed using the pubic domain NIH Image program, and the horizontal and vertical components were calculated automatically. The mean value of maximum slow phase velocity (MSPV) in the normal guinea pigs and guinea pigs with vestibular disorder was 37.288±9.423 degree/sec and 9.786±2.758 degree/sec respectively. There was a significant correlation between the PRN number and MSPV.We consider that this system makes it possible to evaluate vestibular function in animal models easily and inexpensively.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
