Abstract

Intrathyroidal parathyroid carcinoma is very rare. To our knowledge, only 2 cases of intrathyroidal parathyroid carcinoma had been reported in Japan. Recently, we encountered a case of hyperfunctioning Intrathyroidal parathyroid carcinoma.A 16-year-old female had complained of thirst, polyposia and polyuria for 6 months. An elastic hard nodule 2 cm in diameter was palpated on the right thyroid lobe. The serum calcium level was 16.2 mg/dl and serum intact-PTH level was 1100 pg/ml (normal value in serum: 10-60 pg/ml). Based on ultrasonography and 201T1 subtraction 99mTc scanning, primary hyperparathyroidism due to a hyperfunctioning parathyroid gland in the right thyroid lobe was suspected. A right lobectomy and local dissection was performed. The tumor was histologically diagnosed as an Intrathyroidal parathyroid carcinoma. The patient was asymptomatic and normocalcemic 29 months after surgery.

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