Abstract

Improved diagnostic and treatment techniques for malignant tumors and increased numbers of elderly patients have led to the detection of greater numbers of multiple primary cancers. We describe our experience with a case of synchronous primary triple cancers. Thyroid cancer was discovered during treatment for tongue cancer, following a bladder cancer.After the diagnosis of tongue cancer, the recurrence of bladder cancer was detected. The recurrent bladder cancer was treated first, followed by the tongue cancer. Radical neck dissection for the tongue cancer revealed occult lymph node metastasis from thyroid cancer. Although thyroidectomy was scheduled to be performed after treatment for the tongue cancer, the second recurrence of bladder cancer was diagnosed. After therapy for this bladder cancer, thyroidectomy was performed.Treatment for synchronous primary triple cancers should be planned to achieve the best outcome for each cancer. Outcome is poorer for patients with multiple primary cancers than for those with single primary cancer. To improve the outcome of synchronous primary cancers, early detection, prompt and effective treatment, and close follow-up of the patient's course, including examination of predilection sites, are considered important.

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