Abstract
Particle size control of emulsion is very important for keeping its stability and giving it new functional role. Porous glass membrane prepared by phase separation of a glass composition, is found to be available as emulsifying element in order to obtain. monodispersed emulsion with different particle sizes and useful W/O/W emulsion, water in oil in water type in superior high yield. We called this technology “membrane emulsification”. Applications of the membrane emulsification to drug delivery systems were carried out under cooperative research with Miyazaki Medical College. According to clinical administration, W/O/W emulsion drug encapsulated anti-cancer reagent in inner droplets, was surprisingly effective for both terminal and multi originated in hepatocellular carcinoma when the drug was injected to suffered liver through a catheter inserted in liver artery. Another applications are tried and developed in some academia and various enterprises.
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