バカンピシリン錠内服により生じた急性食道炎の１例

Abstract

A case of drug-induced esophagitis is presented. A bacampicilin tablet was clinically thought to be the causal drug for this case. This patient is 28 years old female, and she swallowed the tablet without fluid just before lying in bed. Symptoms appeared 4 hours after taking the drug. The symptoms were odynophagia and retrosternal pain. Endoscopically, several stripes of whitish belag were attached on esophageal mucosa along almost all of its length, and erosive lesions were found at 25cm and 40cm from the incisors. We diagnosed this esophagitis of Bacampicilin-induced esophagitis because of the characteristic history and the relationship to the drug. The symptoms disappeared rapidly and no scar or constriction was left endoscopically. The pH, osmolarity, and electric conductivity of this drug were not significantly high for inducing esophageal lesions, and the pathogenesis of this drug was not identified.But by fact that even the drug of such low pathogenesis could induce esophageal lesion depending on swallowing method, we would say that we should pay attention to the method of medication.