Abstract
The quality of 3 kinds of commercial prednisolone intact tablets was evaluated by weight variation, content uniformity and dissolution, and that of tablet halves, prepared by manual division of tablets along the score, by weight variation and dissolution. These tests were made according to the method prescribed in JP X. Following results were obtained: 1) All of the 3 kinds of intact tablets met the quality standard prescribed in JP X. 2) In each of the 3 kinds of tablets, no difference was found in dissolution patterns between intact tablets and tablet halves. 3) In each of the 3 kinds, percentage range of weight variation was wider in tablet halves than in intact tablets.
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