Abstract
General review on the recent progress of glycosphingolipids was described both in various kinds of blood cells. and in the nervous tissues. First, the cell membrane glycosphingolipids were summarized and discussed as important markers for the maturation and differentiation from immature blood cells to mature myeloid and lymphoid cells, erythrocytes and platelets, as specific ligands to some selectins for cell-cell recognition and as roles of immunological responses.Second, the biological significance of myelin lipids, particularly cerebroside and sulfatide, changes of neuronal gangliosides in the development of neuronal cells, abnormal gangliosides in the brain tumors and biological activities of gangliosides were mentioned.
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