Abstract

Malignant fibrous histiocytosis (MFH), the most common soft-tissue sarcoma, appears commonly in adult proximal limb muscles and retroperitoneum, but rarely in the nasal sinus. We report a case with a good outcome thanks to cyberknife therapy of maxillary sinus MFH relapsing frequently after surgical and radiation therapy. An 80-years-old man was seen for tumors filling the right nasal cavity and from the maxillary sinus to the nasal cavity found in computed tomography (CT). We partially excised the right maxilla. Pathological tissue inspection showed malignant fibrous histiocytosis. Despite postoperative 72 Gy radiation, the tumor relapsed twice more, after which we used a cyberknife in therapy, eliminating the tumor. No tumor has recurred in the 18 months since.

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