慢性脑供血不足患者的脑血管功能分析

Abstract

目的：研究慢性脑供血不足患者的脑血管功能情况。方法：采用CBA CV300型脑血管功能(CVHI)检测仪分别对120例慢性脑供血不足患者和60例正常对照组进行测定，分析相关指标。结果：慢性脑供血不足(CCCI)患者，随着年龄的增长，平均血流量(Qmean)、最大流速(Vmax)、最小流速(Vmin)、平均流速(Vmean)和差压(DP)等呈显著下降趋势，外周阻力(Rv)、特性阻抗(Zcv)、脉搏波速(Wv)、动态阻力(DR)、临界压(CP)等指标呈现显著升高趋势。CCCI患者的积分值、流速和流量等明显低于对照组，但Rv、Wv及Zcv等明显高于对照组，差异有统计学意义(P < 0.05)。结论：慢性脑供血不足是动脉粥样硬化所致，脑血管功能受损明显，卒中发病风险增加。 Objective: To study the Cerebrovascular Function in patients with chronic cerebral circulation insufficiency (CCCI). Methods: 120 patients diagnosed as CCCI were assigned in test group, and 60 healthy people were in normal control group; they were given CBA CV300 Cerebrovascular hemodynamic indexes (CVHI) examination, and analysis of related indicators. Results: In CCCI, with the age increaing, cerebrovascular hemodynamic synthesized index, including quantity of mean blood flow (Qmean), velocity of maximum blood flow (Vmax), velocity of minimus blood flow (Vmin), velocity of mean blood flow (Vmean), pulse wave velocity (Wv), characteristic impedance (Zcv), resistance of vascular (Rv), development resistance (DR), capillary pressure (CP), pressure difference (DP). The numbers of Qmean, Vmax, Vmin, Vmean and DP appeared to obviously decline, but the numbers of Rv, Zcv, Wv, DR and CP appeared to obviously raise. The CCCI patients’ cerebrovascular hemodynamic synthesized score (CVHS), flow velocity and flow rate are significantly lower than the control group, but the Rv, Wv and Zcv, significantly higher than the control group, the difference was statistically significant. Conclusions: CCCI is the result of atherosclerosis, and Cerebrovascular function was damaged obviously, the risk of stroke is increasing.