益气滋阴润肺汤结合西药治疗肺结核的临床疗效研究

Abstract

目的：观察中西医结合方法治疗肺结核病的临床疗效。方法：将100例肺结核病的患者随机分为两组，其中治疗组57例及对照组43例。两组均予常规抗痨治疗；治疗组在常规治疗基础上加服益气滋阴润肺汤，疗程为6个月。治疗期间观察临床症状改善、痰菌转阴、空洞缩小及病灶吸收率等情况；观察两组患者治疗前后外周血IFN-γ(γ-干扰素)、白介素13(IL-13)、肿瘤坏死因子(TNF)、透明质酸(HA)的水平变化、药物不良反应改善情况。结果：治疗6个月后治疗组在痰菌转阴率、空洞缩小率、病灶吸收率、临床症状改善率等方面明显优与对照组(P Objective: To observe the clinical curative effect of traditional Chinese and Western medicine treatment of pulmonary tuberculosis. Method: To divide randomly 100 cases of pulmonary tu-berculosis into two groups, 57 cases in treatment group and 43 cases in the control group. The two groups were given conventional anti-tuberculosis treatment; the treatment group was based on routine treatment with Yiqi Ziyin Runfei decoction for 6 months. During the treatment, the im-provement of clinical symptoms, the negative conversion of sputum, diminished cavity and lesions absorption rate will be observed. Two groups were observed before and after treatment about level changes of peripheral blood IFN-γ (γ-interferon), interleukin 13 (IL-13), tumor necrosis factor (TNF), hyaluronic acid (HA), and the situation of drug reaction improvement. Results: After 6 months of treatment in treatment group, the sputum negative conversion rate, diminished rate of cavity, lesions absorption rate, clinical symptom improvement rate were significantly better than that in the control group (P