類象牙質の形成を伴った腺様歯原性腫ようの１例

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The adenomatoid odontogenic tumor (AOT) is a rare benign tumor. In this paper, a case of AOT which was histologically different from the previously reported cases was described.A 34 year-old male was referred for evaluation of a swelling in the mandible. The patient had been aware of the swelling for several months but never felt pain or paresthesia. The patient's past medical history was noncontributory. Local examinations disclosed an expansion of the cortices of the lower anterior region. The overlying mucosa was normal in color and texture. Radiographs revealed a radiolucent monolocular lesion in the anteriorpremolar area of the mandible. The lesion was interpreted as a benign tumor of the mandible. Under general anesthesia, surgical enucleation and curettage were carried out. The teeth from the right central incisor to the left premolar were extracted. Pathological diagnosis of the surgical specimen was an adenomatoid odontogenic tumor associated with dentinoid formation. The patient has been free of disease for two years after the surgery. From the following analysis of the previously reported cases, the current case was characterized by several unusual features, such as sex (male) and age (34 years old) of the patient, location of the lesion (mandible), absence of the impacted teeth and presence of dentinoid formation.From a search of the Japanese literature, the authors chose 84 well-documented cases of AOT including our own case to characterize clinical features of AOT among the Japanese. The following analysis is based on our study.1. AOT occurs most frequently in the second decade of life, though cases have been reported in the range of 3-46 years of age. The mean age is 18. 2 years.2. AOT affects females with greater frequency than males, a ratio of 3. 4: 1.3. The maxilla is involved more frequently than the mandible, a ratio of 1. 3: 1.4. Sixty-seven percent of AOT is associated with the impacted teeth and the canine is most frequently affected (58.9%).5. AOT is usually asymptomatic and causes jaw enlargement.6. AOT often resembles a follicular cyst radiographically.7. The size of AOT is less than 3.0 cm in diameter.8. Calcified material is usually present within AOT (96.4%).9. AOT does not show invasive tendency, metastasis and malignant transformation.10. Enucleation is a curative treatment for AOT.